Renal Transplant Rejection

Introduction: Determining if the cause of renal allograft dysfunction in the early post transplant period is due to rejection or other reasons is a daunting task for the clinician. Clinical signs and symptoms alone are not helpful in clearly distinguishing the numerous causes of renal dysfunction. Various noninvasive tests including imaging studies have also been unsuccessful in distinguishing rejection from other causes.1 Renal allograft biopsy has, therefore, emerged as a key element in aiding in the accurate